Objective: The objective of this thesis was to establish an experimental 3D culture system based on liver cancer (HepG2) cells in a gelatin scaffold and …
Recent advancements in the techniques used for developing in vitro three-dimensional cell cultures, such as bioprinting or microtissue formation, has offered a more accurate representation …
Human glioblastomas develop within the brain parenchyma in which there is continuous interaction of glioma cells with axon fibers, glial cells and endothelial cells. This …
In this research, two inhibitors of MMPs were added to dermal fibroblast tissue rings that were allowed to self-assemble and produce their own ECM. One …
Standard toxicity testing of chemicals to assess risk in humans is commonly done on animals. The problem, however, is that animals have been found to …