This thesis advances visualization design research by developing and evaluating new theoretical knowledge and computational techniques, which target the rising complexity of data and growing …
Non-allelic homologous recombination (NAHR) plays a major role in genome rearrangement and is implicated in numerous genetic disorders. But detection of NAHR poses a serious …
This dissertation presents new computational approaches toward the virtual histology of white-matter microstructures and new visualization and interaction techniques for identifying and segmenting white-matter anatomy. …
Over the past decade, genome-wide associations studies (GWAS) and other methods have used human genetic data to successfully identify thousands of genomic elements underpinning complex …
Sexual reproduction typically involves fusion of haploid gametes to form diploid cells, which subsequently undergo meiosis to regenerate the haploid form. Despite the ubiquity of …
We develop new algorithms for training nonparametric clustering models based on the Dirichlet Process (DP), including DP mixture models, hierarchical Dirichlet process (HDP) topic models, …
DNA replication initiates from any given origin at most once per cell cycle to ensure perfect duplication of the hereditary material. DNA re-replication occurs when …