The CACNA1C gene has the potential to generate many CaV1.2 voltage-gated calcium channel protein isoforms. CaV1.2 proteins are widely expressed throughout the body and have …
Abstract of “Contributions to the Relationship Between Circadian Rhythm Protein Dysfunction and Epilepsy—CLOCK and the PAR bZIP Transcription Factors” by Luis Antonio Goicouria, Ph.D., Brown …
Mutations in the SLC13A5 gene, which encodes a plasma membrane citrate transporter, result in developmental epileptic encephalopathy (DEE25), a disorder characterized by infantile multi-focal seizures, …
Alterations in metabolism, sleep patterns, body composition, and hormone status are all key features of aging. While the hypothalamus is a well-conserved brain region that …
The immune dysfunction induced by alcohol use has severe and devastating health consequences. Despite extensive research characterizing the widespread effects of alcohol consumption on the …
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity/impulsivity. While ADHD has a high degree of heritability, how rare genetic …