In this thesis, the potential success of a novel drug delivery system (PDAL DDS) in the current antifungal DDS market was evaluated. Focus was placed …
Background: For some patients with severe, treatment-resistant obsessive-compulsive disorder (OCD), neurosurgical interventions may be considered. While a few studies have assessed both patient and provider …
Abstract of Computational Methods for Evaluating FUS Protein Mutation Pathology, by Amber Chevannes, Sc.M, Brown University, May 2019. There are a number of mutations within …
The safe and economical disposal of electronic waste (E-waste) is a major issue worldwide, as consumption of electronics continues to rise with no end in …
When exposed to pressures below and above their glass transition temperature (Tg) and melting temperatures (Tm) over time, both the amorphous and crystalline regions of …
The revolutionization of capillary electrophoresis (CE) technology has increased research into CE-related issues on long read and ultra-long read lengths for next-generation sequencing (NGS). An …
Cells are rich in a variety of diagnostic information, from morphology to nucleic acid, protein, and metabolite composition. Cells possess more data than any other …
Glioblastoma, classified by the WHO as a grade IV brain tumor, displays highly aggressive and infiltrative properties. Despite the low incidence of the disease as …
The brain is a highly-privileged organ within the body. Evolution has ensured that access to brain tissue is tightly regulated against or completely impenetrable to …
Abstract of “The chromatin and transcriptional landscape of senescent cells”, by Steven W. Criscione, Ph.D., Brown University, May 2017 Senescent cells are recognized as one …
The stromal vascular fraction (SVF) is a heterogeneous population of cells that resides in adipose tissue. It includes adipose-derived stem cells (ASCs), which work synergistically …
Major depressive disorder (MDD) currently affects more than 21 million people globally making it one of the most prevalent neurological conditions worldwide. Current pharmacological treatment …
Microsphere drug delivery systems still face many hurdles specific to gastrointestinal uptake. Human physiological components are difficult to properly emulate and test without the usage …