Pseudogymnoascus destructans is the invasive fungal pathogen responsible for White-Nose Syndrome (WNS), a devastating disease affecting North American bats. WNS has led to the loss …
Manganese (Mn) is an essential dietary nutrient. However, Mn excess can cause irreversible neurological damages often referred to as manganism. While Mn excess is typically …
Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including development, metabolism, stress responses and aging. Drosophila melanogaster IIS is propagated …
Data for tables and figures from dissertation "Mitonuclear genotype, tissue type and sex modify the effects of rapamycin on transcription and metabolism" by John C. …
It has been known that early embryos are largely dependent on the Warburg Effect – a glycolysis-dependent metabolism – for energy. Yet, recent studies in …
Due to medical advances, premature infants born as early as 22 weeks of gestation can survive. Yet, their lungs are underdeveloped and unable to diffuse …
The gut microbiome is the assemblage of symbiotic microbes inhabiting distinct ecological niches within the host that participate in key physiological functions such as energy …
Understanding how cellular activities impact genome stability is critical to multiple biological processes including tumorigenesis and reproductive biology. The fungal pathogen Candida albicans displays striking …
Aging is generally defined as the progressive and time-dependent loss of function accompanied by increasing vulnerability to diseases and mortality. In particular, aging is associated …
Abstract of Sigma-2 Receptor-Mediated Changes in Metabolism and Calcium Signaling, Degree ScM, Brown University, May 2019 Sigma receptors are a pharmacologically distinct family of membrane-bound …
Transposable elements (TEs) are parasitic mobile sequences of DNA that make up large percentages of their host genomes. Because of their ability to move about …