Transgenic neuromodulation tools (i.e., optogenetics and chemogenetics) enable the manipulation of brain activity using targeted genetic delivery strategies for transducing specific cells to produce transgenic …
Animal behavior is driven by perception of biological need and environmental context. Internal representations of the external world help us to interact with and navigate …
In this thesis work, we have presented the concept and fabrication of the single coaxial optrode. Its dual functionality of simultaneous light delivery and electrophysiological …
The perirhinal cortex (PER) has a well-established role in identification and recognition of objects. Our lab previously provided evidence that neuronal activity in PER may …
Neuroprosthesis research aims to enable communication between the brain and external assistive devices while restoring lost functionality such as occurs from stroke, spinal cord injury …
Epilepsy is a common neurological disorder characterized by the recurrence of spontaneous seizures. However, the mechanisms of transition into seizures are still unclear. A better …
The brain's neurotransmitter system is of vital importance to the proper functioning of the brain. In particular, neurotransmitter dopamine has drawn considerable research interest in …
Our ability to detect and perceive pain is driven by complex interactions that occur across the central and peripheral nervous systems. By understanding how neural …
The neural networks consisting of the axonal tracts that interconnect the thalamus and the neocortex are central to information processing where the thalamus acts as …
Recording and modulation of large neuronal populations are essential for uncovering the dynamical properties of complex neural circuits. In the last few decades, various optical …
Deep brain stimulation (DBS) is an effective treatment for the mid/late stage Parkinson’s disease (PD), which significantly reduces the dopamine medication and improves motor symptoms. …