Sepsis is defined as a state of life-threatening organ dysfunction due to dysregulated host response to infection. Because of its complex pathogenesis, sepsis is difficult …
Beta-glucans are glucose polymers found of the fungal cell wall. Beta-glucans have immunological effects and can stimulate innate immune cells. Priming immune cell function can …
Neonatal mortality rates in Haiti are among the highest in the Western hemisphere. Few mothers deliver with a skilled birth attendant present, and there is …
This dissertation focuses on the response of liver sinusoidal endothelial cells (LSECs) to experimental sepsis in order to better understand the pathologic processes contributing to …
Sepsis is a deadly inflammatory condition that initially results in an acute hyper-inflammatory state, but eventually leads to a state of ‘late sepsis’ immune-suppression in …
Sepsis is a life threatening condition that elicits a dysregulated and damaging immune response, which in turn leads to tissue damage and Multiple Organ Dysfunction …
Sepsis continues to affect millions of people around the world, and the incidences are increasing. Sepsis is difficult to treat given the multi-factorial complications associated …