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Brown University Theses and Dissertations

Brown University Library archives dissertations in accordance with the Brown Graduate School policy.

For dissertations published prior to 2008, please consult the following Dissertation LibGuide

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Items (1-4) out of 4 results

Developing a Three-Dimensional Brain Microtissue Model of Ischemic-Reperfusion Injury

Description:
Stroke is a devastating medical emergency caused by a lack of blood flow to a particular area of the brain. Even short interruptions in blood …
Year:
2023
Contributor:
McLaughlin, Rachel M (creator)
Hoffman-Kim, Diane (Advisor)
Lipscombe, Diane (Reader)
Webb, Ashley (Reader)
Thorne, Robert (Reader)
Brown University. Department of Neuroscience (sponsor)
Genre:
theses
Subject:
Image analysis
Brain
Stroke
3D Cell Culture
ischemic-reperfusion
Central nervous system
Collection:
Neuroscience
Theses and Dissertations
Full Record

Identifying Interleukin 6 as a Marker of Central Nervous System Injury Following Susatined Compressive Traumatic Brain Injury in a 3D Cortical Microtissue Model

Description:
Traumatic brain injury (TBI) is a major cause of death and disability around the world. In the USA alone, TBI leads to more than 586 …
Year:
2024
Contributor:
Roy, S. Austin (creator)
Hoffman-Kim, Diane (thesis advisor)
Brown University. Neuroscience (sponsor)
Genre:
theses
Subject:
Central nervous system
Traumatic Brain Injury
TBI
Interleukin-6
IL-6
CNS
Inflammation--Mediators
Collection:
Neuroscience
Theses and Dissertations
Full Record

In Vitro Modeling of the Central Nervous System: Towards Optimized Cell-based Therapies

Description:
Cell-based therapy is a promising treatment option for central nervous system (CNS) disease and injury, but therapy strategies require optimization to achieve clinical improvement. The …
Year:
2015
Contributor:
Dingle, Yu-Ting Liu (creator)
Hoffman-Kim, Diane (Director)
Morgan, Jeffrey (Reader)
Darling, Eric (Reader)
Coulombe, Kareen (Reader)
Kaplan, David (Reader)
Brown University. Biomedical Engineering (sponsor)
Genre:
theses
Subject:
mouse embryonic stem cells
in vitro differentiation
dopamine neurons
3D neural culture
neural spheroids
stem cell transplantation
Stem cells--Transplantation
Central nervous system
Collection:
Biology and Medicine
Biomedical Engineering
Theses and Dissertations
Full Record

New Insights into Nerve Regeneration in the Central Nervous System (CNS): Response of Rat Hippocampal Neurons to Chemical and Electrical Cues

Description:
To improve the capability of nerve regeneration following traumatic brain injuries, neurodegenerative diseases, and neurological disorders, it is essential to understand the mechanism that regulates …
Year:
2013
Contributor:
Kim, Kwang-Min (creator)
Palmore, Tayhas (Director)
Zimmerman, Anita (Reader)
Tripathi, Anubhav (Reader)
Hurt, Robert (Reader)
MacDonald, John (Reader)
Brown University. Biomedical Engineering (sponsor)
Genre:
theses
Subject:
Nerve regeneration
Hippocampal neuron
Nervous system--Regeneration
Central nervous system
Collection:
Biology and Medicine
Biomedical Engineering
Theses and Dissertations
Full Record
  • 1

Items (1-4) out of 4 results