Back to Results

A Historical Analysis of the Searchable NeuroNex Database of Bioluminescent Molecules: The Annual Biomedical Research Conference for Minority Students (ABRCMS) Presentation Poster and Pre-Recorded Link

Full Metadata

Overview

Year:: 2020
Contributor:: Louis, Priscilla (Author); Bartholomew, Brazil (Author); MacIntyre, Cameron (Author); van der Merwe, Rochelle (Author); Roberts, Mia (Author); Allen, Justine (Author); Friedman, Nina (Author); Moore, Christopher (Author)
Subject:: Bioluminescence; Database; Luciferase; Historical analysis
DOI: https://doi.org/10.26300/24ft-p829

Files

- View MODS File
- Download MODS File
ViewMODS
- View PDF File
- Download PDF File
ViewPDF

Description

Abstract:: As bioluminescence becomes increasingly significant to imaging and manipulating neurons in the brain, there presents a need for a database that can concisely present bioluminescent molecules in a simplified construct for researchers to access freely. The NeuroNex Bioluminescence Database lists bioluminescent molecules, their publication sources, and their molecular properties with specifics upon its compatible substrates, peak emission spectra, endogenous organism, size, signal, and more. Under the implications of this toolbox, neuroscientists and researchers may be better equipped to apply specific and appropriate bioluminescent molecules to their individual research projects quicker and more efficiently. A historical analysis of the database was conducted after obtaining nearly one hundred different bioluminescent molecules from prior publications. Due to the lack of technology and other unknown factors, earlier works lacked in the specification of molecular properties. Whereas, recent works were more elaborate on these properties. This may suggest that the first luciferases, or bioluminescent molecules, discovered may be the ones we know the least about. A future direction for scientists today is to use advanced technology to re-approach earlier works and elaborate on their properties to expand the field of bioluminescence.
Notes:: The NeuroNex Technology Hub is supported by the National Science Foundation (NSF) and its Division of Biological Infrastructure under award 1707352 and National Heart, Lung, and Blood Institute of the National Institutes of Health under award 5R25HL088992-14.

Content

Skip item content viewer

Access Conditions

Use and Reproduction: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License

Citation

Louis, Priscilla, Bartholomew, Brazil, MacIntyre, Cameron, et al., "A Historical Analysis of the Searchable NeuroNex Database of Bioluminescent Molecules: The Annual Biomedical Research Conference for Minority Students (ABRCMS) Presentation Poster and Pre-Recorded Link" (2020). NeuroNex Data and Research Products. Brown Digital Repository. Brown University Library. https://doi.org/10.26300/24ft-p829

Relations

Has Parts:

A Historical Analysis of the Searchable NeuroNex Database of Bioluminescent Molecules
- Type: Video
- Order:
- View
A Historical Analysis of the Searchable NeuroNex Database of Bioluminescent Molecules
- Type: Stream
- Order:
- View

Collection:

NeuroNex Data and Research Products

This collection contains publicly available research products, including data, codes, and publications, among others. The NeuroNex Technology Hub is supported by the National Science Foundation (NSF) and its Division of Biological Infrastructure under Award No. 1707352.
...