ATOMICS Clinical Correlate (ATOMICS-CC) Multi-Parametric Alerts (MPAs)


The PERSEUS ATOMICS Clinical Correlate (ATOMICS-CC)research program acquired ED bedside patient monitor datastreams continuously from the study area and displayed specific elements on a remote-mirroring dashboard display in the ED research office. Research assistants used this setup to screen for potential subjects based on whether they met inclusion criteria, as follows: A patient who triggered two or more standard SPAs that all occurred within a 15-minute "concurrence" window was enrolled into the experimental multi-parametric alert [MPA] group, e.g., tachycardia alarm for HR 135 bpm at 02:51:48 and hypotension alarm for BP 78/50 mmHg at 02:57:33. The specific window length was selected to a.) focus on the temporal proximity of discrete vital sign abnormalities as a reflection of severe underlying pathology impacting interconnected cardiopulmonary systems, and b.) reduce the likelihood of queries detecting overlapping alarms that were set off by two different patients during a rapid ED room turnover.
This research was supported by the Agency for Healthcare, Research and Quality (AHRQ) under award number R18HS022860.


Kobayashi L., Oyalowo A., Agrawal U., et al., "ATOMICS Clinical Correlate (ATOMICS-CC) Multi-Parametric Alerts (MPAs)" (2019). Brown University Open Data Collection. Brown Digital Repository. Brown University Library.



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