The brain’s ability to attribute valence to sensory stimuli in our environment and modulate these associations to reflect its current state is essential for goal …
Adverse experiences in childhood, ranging from neglect to resource scarcity to abuse, alter developmental trajectories and increase risk for reward-related psychopathologies. In humans, exposure to …
Background- Angelman syndrome (AS) is a severe cognitive disorder caused by loss of neuronal expression of the E3 ubiquitin ligase UBE3A. Brain-derived neurotrophic factor (BDNF) …
The perirhinal cortex (PER) has a well-established role in identification and recognition of objects. Our lab previously provided evidence that neuronal activity in PER may …
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the upper and lower motor neurons resulting in weakness, paralysis and death within two to five …
The basal ganglia has been implicated in motivational behavior, reinforcement learning, reward seeking, and action selection. The dual nature of these behaviors, i.e. encouragement vs. …
Neocortical oscillations in the gamma range (30 Hz- 80 Hz) have been shown to be predictive of the allocation of attention and increased sensory processing. …
In early postnatal life, infants are faced with complex changing and noisy environments that require learning and action. Yet, relatively little is understood about how …
Data from lesion studies, anatomical connections, and functional recordings suggest that the postrhinal cortex (POR) has a role in encoding and recognizing context for memory. …
Stress is a known risk factor for a number of neuropsychiatric disorders such as depression and addiction. Characteristic of such disorders are deficits in corticostriatal-mediated …
Prenatal exposure to valproic acid (VPA), a commonly prescribed antiepileptic medication, is known to greatly increase risk for autism and other neurodevelopmental disorders (NDDs). Prior …
The function of the retrosplenial cortex (RSC) in human cognition is a topic of rising interest in cognitive and behavioral neuroscience. So far, however, there …
