Autism constitutes a diverse set of disorders thought to affect neuronal connectivity and circuit development. Its etiology is heterogeneous, but certain rare genetic mutations have …
Polyamines are endogenous molecules involved in cell damage following neurological insults, although it is unclear whether polyamines reduce or exacerbate this damage. We used a …
Notch signaling is a key regulator of developmental processes in many metazoans. However, it is also active in the adult nervous system of animals ranging …
The modern study of animal camouflage has received renewed interest in the past two decades. Rapid adaptive camouflage is particularly interesting because it allows us …
Deep neural networks (DNNs), which are based loosely on the ventral stream pathway of the primate visual system, are good models of the visual system …
Autism spectrum disorder (ASD) is characterized by impairments in social affective engagement. The present study uses a social press, in the form of a mild …
The relationship between alcohol and emotion is extremely complex. Prolonged heavy alcohol consumption and acute alcohol administration both affect emotional processing in the brain. In …
CaV2.2 voltage-gated calcium channels (CaVs) are expressed at presynaptic terminals in most central and peripheral neurons where they control the calcium (Ca2+) entry that triggers …
Increased oscillations and synchronized behavior in the Subthalamic Nucleus (STN) and nearby structures have been linked to the progression of Parkinson’s Disease (PD), and this …
In the developing nervous system growing axons are guided to their correct targets by the interaction between receptors expressed on axon growth cones and environmental …
Animal behavior is driven by perception of biological need and environmental context. Internal representations of the external world help us to interact with and navigate …
Obsessive-compulsive disorder (OCD) is a chronic condition characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions) that interfere with daily functioning. These intrusive thoughts and …
Ovarian steroids have been shown to modulate cognitive functions in both animals and humans, but results are inconsistent. The variability of the findings suggests that …
Visuomotor adaptation is a process engaged in everyday settings because of its critical role in adjusting visually-guided actions, such as reaching. Two processes contribute to …
Alternative splicing in the nervous system is an important regulator of neuronal function. CaV2.2 calcium channels control neurotransmission and are extensively alternatively spliced in a …
Spinal muscular atrophy (SMA) is an autosomal recessive neurological disorder characterized by loss of lower motor neurons with resulting skeletal muscle atrophy, and is one …
Epilepsy is the most common neurological disorder affecting a significant portion of the United States (Kabat and Przemysław 2012). The involvement of Circadian Locomotor Output …
The role of myelination in allowing for efficient neural impulse transmission in the central nervous system has been widely studied, but its roles in other …
The CACNA1C gene has the potential to generate many CaV1.2 voltage-gated calcium channel protein isoforms. CaV1.2 proteins are widely expressed throughout the body and have …
Afferent inputs to the ventral tegmental area (VTA) control reward-related behaviors through regulation of dopamine neuron activity. Although the nucleus accumbens (NAc) has long been …