Strict regulatory mechanisms ensure that the cell’s genome is perfectly duplicated. In eukaryotic cells, origins of replication fire once and only once per cell cycle. …
Abstract of ‘Ecdysone-Regulated DNA Amplification in Sciara coprophila’, by Léo Kadota, Sc.M., Brown University, May 2017. The eukaryotic genome contains thousands of origins (ORIs) of …
DNA replication initiates from any given origin at most once per cell cycle to ensure perfect duplication of the hereditary material. DNA re-replication occurs when …
Innate regulatory mechanisms ensure that an origin of replication activates at most once per cell cycle. An override of this control results in multiple firings …