Sex determination is an essential, and highly variable process, of organismal development. Looking for common threads used in evolution to determine sex is difficult simply …
Age is a fundamental aspect of biology that underlies the efficacy of a broad range of functions. Identifying determinants for how quickly or slowly we …
Transposons are parasitic DNA sequences that pose threats to genome stability across a range of eukaryotes. To defend against transposition into essential genes and destabilizing …
Assisted reproductive therapy and fertility preservation techniques such as freezing eggs are increasingly used to improve or safeguard human reproduction worldwide, yet what factors govern …
Resistance to starvation is a classical complex trait, where varying genetic and environmental landscapes can greatly modify an animal’s ability to cope. In this study, …
Cytoplasmic mRNA localization is understood as an important biological strategy for establishing cell and developmental polarity in a variety of organisms and cell types. In …
Christianson syndrome (CS) is an X-linked, monogenic, neurological disorder caused by mutations in SLC9A6, the gene encoding Na+/H+ exchanger 6 (NHE6). Symptoms of CS include …
RNA-binding proteins (RBPs) interact with a network of other proteins to form ribonucleoprotein (RNP) complexes, which are critical players throughout the lifecycle of RNA. Dysfunction …
An organism’s survival relies on its ability to navigate through the environment. To perform this task, animals must construct a map of space and translate …
The human genome is organized in a hierarchical manner from higher order to lower order structures. At the highest level are chromosome territories that are …
RNA localization and biomolecular condensate formation are key biological strategies for organizing the cytoplasm and generating cellular and developmental polarity. During Xenopus oocyte development, RNAs …
Candida species are a group of opportunistic fungal pathogens that cause life-threatening illness in the immunocompromised, but typically inhabit the human gastrointestinal tract as a …
Advances in sequencing technologies in the last decade have enabled us to profile various genomic features at the single-cell resolution, such as gene expression and …
With increasing temperature extremes during critical crop reproductive periods, crop yield will decline, and food stability will be threatened. As flowering plants, crop reproduction depends …
DNA replication initiates from any given origin at most once per cell cycle to ensure perfect duplication of the hereditary material. DNA re-replication occurs when …
Successful plant reproduction is the lynchpin of agricultural food production. With high susceptibility to climatic variations and other stress conditions, plant reproduction demands further investigation …
Aging is the one thing that no person has survived. This complex phenotype is driven by many changes, including an increased prevalence of cellular senescence. …
Transposable elements (TEs) are parasitic mobile sequences of DNA that make up large percentages of their host genomes. Because of their ability to move about …