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Description:: Objective: Traumatic brain injury (TBI) results when external forces exert strain on the brain, resulting in cell death, inflammation, and long-term neurological effects. To screen …
Year:: 2025
Contributor:: Vecchio, Francesca B (creator); Hoffman-Kim, Diane (Advisor); Kesari, Haneesh (Reader); Mayoral, Sonia (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Biomechanics; traumatic brain injury; high strain-rate deformation; 3D Cell Culture; in vitro; Rat Cortical Microtissues; 3d Bioprinting
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: Despite decades of research, Alzheimer’s disease (AD) remains a severe public health crisis accounting for 60-80% of dementia cases worldwide. Growing evidence implicating microglia dysfunction …
Year:: 2025
Contributor:: Brown, Sophie Corinne (creator); Borton, David (Advisor); Huang, Yu-Wen (Reader); Frost, Bess (Reader); Mayoral, Sonia (Reader); Hoffman-Kim, Diane (Reader); Brown University. School of Engineering (sponsor)
Genre:: theses
Subject:: Alzheimer's disease; microtissue; 3D Cell Culture; Microglia; neuroinflammation
Collection:: Engineering; Theses and Dissertations

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Description:: Alzheimer’s disease (AD) is the most common form of dementia, estimated to affect over 6 million individuals in the United States in 20241,2. Despite its …
Year:: 2024
Contributor:: Drexler, Abigail Rose (creator); Borton, David (Advisor); Mayoral, Sonia (Reader); Huang, Yu-Wen Alvin (Reader); Morgan, Jeffrey (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Alzheimer's disease; 3D Cell Culture
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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