The human polyomavirus BK is a clinically relevant virus that causes the diseases Polyomavirus Induced Nephropathy and Hemorrhagic Cystitis in immune suppressed kidney and bone …
In sexual reproduction, fusion of haploid sperm and egg cells (gametes) are required to produce a unique diploid individual that represents the next generation. Despite …
The invasion of foreign pathogens and the development of cancerous cells result in human infections and diseases. The severity of this outcome is dependent on …
The bone morphogenetic protein (BMP) signaling pathway is an essential regulator of developmental and cellular processes. Secreted ligands initiate BMP signaling by binding to a …
CaV2.2 calcium channels are critical regulators of cellular calcium entry in neurons and couple electrical stimulation to neurotransmitter release. These channels are responsible for mediating …
Candida species are a group of opportunistic fungal pathogens that cause life-threatening illness in the immunocompromised, but typically inhabit the human gastrointestinal tract as a …
Cells have a robust protein quality control (PQC) network that ensures proteins reach and maintain their proper fold, and breakdowns in this network result in …