Given the increasing worldwide energy demand and the finite supply of fossil fuels, the development of renewable energy sources is of global importance. The use …
Reversible protein phosphorylation plays a vital role in the regulation of cellular signaling pathways. With recent breakthrough developments in mass spectrometry-based proteomics technologies, including phosphopeptide …
The activation of T-lymphocytes through antigen-mediated T-cell receptor (TCR) clustering is vital in the regulation of the adaptive-immune response and must be properly regulated to …
The basal T cell signaling is important in the T cells maturation and differentiation. The kinase-phosphatase pair Csk and CD45 regulate the basal signaling by …
The prion hypothesis provides an explanation for a diverse collection of previously inexplicable phenomena, ranging from the appearance, progression and spread of neurodegenerative disease in …
Expansion of trinucleotide repeat (TNR) DNA is implicated in several neurodegenerative disorders, including Huntington's Disease (HD). Expansion propensity and disease progression is dictated by repeat …