Src homology region 2-containing protein tyrosine phosphatase 2 (SHP2) is a key enzyme involved in pathways regulating tumor growth signaling. Inhibition of SHP2 has been …
Articular cartilage is a smooth, load bearing tissue that lines the ends of bones in articulating joints. Smooth joint motion is facilitated by synovial fluid, …
Articular cartilage is a smooth, load bearing tissue that lines the ends of bones in articulating joints. Smooth joint motion is facilitated by synovial fluid, …
Abstract of Profiling Cancer Cell Invasion and Plasticity in Biomimetic Materials, by Amanda S. Khoo, Ph.D., Brown University, February 2022 Cancer metastasis is a major …
Abstract of Prototype Design of a Photonic Retinal Prosthesis, by Kenzie Magnan, ScM, Brown University, May 2020. This thesis presented the mechanical and brief optical …
Spinal neuromonitoring is a medical technique that involves monitoring the function of the spinal cord and nerve roots during surgery or other procedures to minimize …
Objective: Females experience ACL tears at disproportionately higher rates potentially due to the effects of the hormone relaxin. To precisely measure ACL biomechanical properties in …
Forces play an important role in physiology and pathology. Throughout development, cellular forces aid in the creation of tissues and organs. In wound healing, cellular …
Optical coherence tomography (OCT) is becoming increasingly popular for neuroscientific study, but it remains challenging to objectively quantify tissue and vascular properties from 3D or …
Caulobacter crescentus is a gram-negative, non-pathogenic, freshwater bacterium which has recently captured the attention of researches in the multidisciplinary study of bioadhesives. C. crescentus is …
Microtissue self-assembly and fusion are biological processes that are important to the fields of tissue engineering and biofabrication and particularly relevant to techniques such as …
3D microtissues are superior to mono-layers of cells grown in 2D because 3D better replicates tissue function and also replicates the natural microenvironments of in …
Patients presenting pathological conditions requiring brain monitoring often undergo EEG examination where a series of electrodes are glued to the scalp. While simple and noninvasive, …
Skin pigmentation is a significant issue with pulse oximetry as several studies have demonstrated pulse oximeters can overestimate the oxygen saturation for people with darker …
Polyethylene is the most popular plastic globally and is used in a wide variety of industry and biomedical applications because of the customizability of its …
The tumor microenvironment is characterized by an acidic pH which confers the expression of more malignant phenotypes in cancer cells such as increased proliferation, migration, …
Abstract Restoring Fecal Continence: An Investigation into Integrating a Synthetic Biomaterial into Colonic Mucosa By Kevin Wood BS, Dickinson College, Carlisle PA, 2011 Thesis Abstract …
Many diagnostic tests are dependent on the effective capture and amplification of nucleic acids. However, the biological samples which contain the target molecules (blood, urine, …
Chemotherapy is one of the most effective breast cancer treatment strategies to date. However, a subtype of breast cancer cells, which were giant in size, …
Brain cancer remains a pervasive public health issue. The use of CNN’s to segment brain tumor images has gained significant traction since 2012; however, most …