Sigma receptors are a pharmacologically defined class of intracellular orphan receptors that bind a variety of psychotropic agents. The endogenous function of the sigma-2 receptor …
Mitochondria carry their own unique genome which must functionally coordinate with the nuclear genome in meeting cellular demands for energy and maintaining homeostatic conditions. This …
Communication between the mitochondrial and nuclear genomes is vital for cellular function. The assembly of mitochondrial enzyme complexes that produce the majority of cellular energy …
Mitochondria are referred to as the “powerhouse of the cell” for their ability to perform oxidative phosphorylation (OXPHOS), but they also perform a diverse array …
The aim of the research presented in this dissertation is to increase our understanding of the development, function, and regulation of innate lymphoid cells in …