The research outlined in this dissertation investigates the role of the miR-181 family of miRNAs in two different contexts: Glioblastoma Multiforme (GBM) and in the …
Neurons have highly developed pathfinding abilities, but in any part of the nervous system, during development or after the challenge of injury, cues provided by …
The cellular complexity of the brain ensures great difficulty in understanding how traumatic injury or neurological disorders affect neural communication and the tissue’s structure. However, …
Three-dimensional brain cultures offer many insights into their in vivo counterparts. Although some activity has been observed at the single cell level, and on a …
We develop three new models of neurovascular coupling at each interface of the neurovascular unit. The neurovascular unit comprises neurons, microvessels, and astrocytes, a type …
The purpose of the current study was to examine the time-course of changes in vascular pericyte and astrocyte coverage and claudin-5 protein expression within the …
Aging is the main contributing factor when it comes to the development of neurological diseases. Astrocytes in the subventricular zone (SVZ) play an important role …