Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with symptom-onset occurring in adulthood. ALS is characterized by progressive degeneration of upper and lower motor …
A central focus of genetics seeks to understand how genotype contributes to phenotype. Simple, single gene traits are generally driven by alleles with additive or …
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects upper and lower motor neurons to cause loss of muscle control. Mutations in specific …
Chitinase 3-Like 1 (CHI3L1) a secreted glycoprotein, has been found to play a role in inflammation, as well as cell survival, growth, and proliferation (Ku …
Splicing and transcription are crucial biological processes involved in development, contributing to the generation of diverse transcripts and proteins. The resulting protein diversity gives rise …