Neurogenesis in the mammalian hippocampus persists throughout adulthood, but the function of newly-born hippocampal cells remains largely unknown. This dissertation investigates the effects of neurogenesis …
Plasma p-tau181 is an increasingly established diagnostic marker for Alzheimer’s disease (AD); however, its precise relationship with brain tau pathology and the neural mechanisms underlying …
Synaptic plasticity is a cellular substrate for learning and memory underlying many behaviors and cognitive function. Dysfunctional synaptic plasticity, both functional and structural, is a …
When groups of neurons are synchronously and rhythmically active, they give rise to electrical oscillations that can be seen in the surrounding extracellular local field …
Precise computation of sensory and contextual information in the mammalian neocortex and hippocampus relies on reciprocally connected networks of excitatory glutamatergic principal cells and inhibitory …