Pseudogymnoascus destructans is the invasive fungal pathogen responsible for White-Nose Syndrome (WNS), a devastating disease affecting North American bats. WNS has led to the loss …
Data set contents: Volcano plots of individual time point differential expression analysis; Western blot analysis of phosphorylated S6 kinase; Heatmaps of gene expression in enriched …
Data set contents: Count table; Individual time point differential expression analyses; Longitudinal time course differential expression analyses; Gene ontology enrichment analysis for OOC~SOC; KEGG pathway …
Data set contents: Volcano plots of the four post-starvation time points compared to starved state for each genotype x treatment time course; Expression profile clustering …
Data set content: Pre-normalization mitochondrial Oxygen consumption rates in response to rapamycin for three mitonuclear genotypes and Mitonuclear genotype alters the impact of rapamycin on …
Data set contents: ANOVA of metabolite levels in female OreR;OreR and sm21;OreR genotypes and ANOVA of metabolite levels in male OreR;OreR and sm21;OreR genotypes.
Manganese (Mn) is an essential dietary nutrient. However, Mn excess can cause irreversible neurological damages often referred to as manganism. While Mn excess is typically …
Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including development, metabolism, stress responses and aging. Drosophila melanogaster IIS is propagated …
Data for tables and figures from dissertation "Mitonuclear genotype, tissue type and sex modify the effects of rapamycin on transcription and metabolism" by John C. …
It has been known that early embryos are largely dependent on the Warburg Effect – a glycolysis-dependent metabolism – for energy. Yet, recent studies in …
Sugar has become a mainstay of contemporary diets. Sometimes visible in the form of sweets and heaping teaspoons of white powder dumped into coffee and …
Due to medical advances, premature infants born as early as 22 weeks of gestation can survive. Yet, their lungs are underdeveloped and unable to diffuse …
The gut microbiome is the assemblage of symbiotic microbes inhabiting distinct ecological niches within the host that participate in key physiological functions such as energy …
Objective: The role of metabolism in development has recently gained broad recognition due to an increasing number of studies in embryo and disease models. However, …
Understanding how cellular activities impact genome stability is critical to multiple biological processes including tumorigenesis and reproductive biology. The fungal pathogen Candida albicans displays striking …
Aging is generally defined as the progressive and time-dependent loss of function accompanied by increasing vulnerability to diseases and mortality. In particular, aging is associated …
Abstract of Sigma-2 Receptor-Mediated Changes in Metabolism and Calcium Signaling, Degree ScM, Brown University, May 2019 Sigma receptors are a pharmacologically distinct family of membrane-bound …
Transposable elements (TEs) are parasitic mobile sequences of DNA that make up large percentages of their host genomes. Because of their ability to move about …