Diffusion-ordered NMR spectroscopy (DOSY) has been established as an efficient means for the separation of the NMR resonances in mixtures of compounds in solution. Despite …
The reactivity and structure determination of various organolithium reagents are described. First of all, we present the development of 13C enriched internal reference system for …
Recently mechanochemical synthesis has attracted our attention since it avoids the use of bulky organic solvents and simplifies reaction processes through grinding or milling. Mechanochemical …
Lithium enolates are used pervasively throughout organic synthesis as versatile carbon nucleophiles to introduce substituents alpha to the carbonyl group in ketones, esters, aldehydes, and …
Solvation state and aggregation state of organolithium complexes are important factors that influence their reactivity. While aggregation state studies of organolithium reagents have been extensive …
Structural characterization of organolithium compounds in solution is an important but challenging task. Solution nuclear magnetic resonance (NMR) and X-ray crystallography are two of the …