Endocrine disruptors are a broad class of toxicants with the ability to alter and/or interfere with normal endocrine signaling. The perinatal period is particularly vulnerable …
Primary ovarian insufficiency (POI) affects 1% of women under 40, and can be induced by ovarian follicle disruption or depletion. Taf4b is a gonadal-enriched subunit …
TAF4b is a gonadal-encriched variant of the general transcription factor complex, TFIID. The studies presented here highlight the specific requirement for TAF4b in female mammalian …