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A phase 1 randomized cross-over drug-alcohol interaction study with the mGluR5 negative allosteric modulator GET73 in healthy male volunteers

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Description:: In an open-label, randomized, crossover study in healthy male volunteers (n=12), we looked to assess the bioavailability of GET73 and of its major metabolite MET2 …
Year:: 2017
Contributor:: Long, Victoria M. (creator); Haass-Koffler, Carolina L. (creator); Goodyear, Kimberly (creator); Loche, Antonella (creator); Cacciaglia, Roberto (creator); Swift, Robert M. (creator); Leggio, Lorenzo (creator)
Genre:: posters
Subject:: Pharmacokinetics; Alcohol
Collection:: Public Health Research Day

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Rational Design of Novel Irreversible Inhibitors for Human Arginase and Applications of Nanoparticles for Catalytic Reactions

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Description:: Parasites have developed a variety of strategies for invading hosts and escaping their immune response. A common mechanism by which parasites escape nitric oxide (NO) …
Year:: 2019
Contributor:: Guo, Xuefeng (creator); Seto, Christopher (Advisor); Basu, Amit (Reader); Sun, Shouheng (Reader); Brown University. Department of Chemistry (sponsor)
Genre:: theses
Subject:: Catalysis; Mass spectrometry; Pharmaceutical chemistry; Organic compounds--Synthesis; Pharmacokinetics
Collection:: Chemistry; Theses and Dissertations

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Items (1-2) out of 2 results