A-to-I RNA editing is the post-transcriptional modification of pre-mRNA transcripts,where specific adenosine residues are converted to inosine by Adenosine DeaminasesActing on RNA (ADARs). This modification …
An exceptional group of aquatic invertebrates makes up Class Bdelloidea. Bdelloid rotifers are the only group of ancient asexual animals known. A second distinction that …
Amyotrophic Lateral Sclerosis (ALS) is a debilitating disease characterized by progressive degeneration and death of motor neurons in the human body, which leads to disability, …
In eukaryotic cells, informational recoding and RNA interference (RNAi) proceed through structurally diverse double-stranded (ds) RNA molecules. Informational recoding of RNA by the catalytic deamination …
The specificity and extent of RNA editing by ADAR enzymes is determined largely by local primary sequence and secondary structural imperfections in duplex RNA. Here, …
Adenosine Deaminase Acting on RNA (ADAR), modifies double-stranded RNA molecules through post-transcriptional hydrolytic deamination of specific adenosines, turning them into inosines (A-to-I RNA editing), which …
Accurate prediction of RNA editing sites requires being able to differentiate genuine edit events from single-nucleotide polymorphism (SNP) events and sequencing machine error events. In …
Far from being solely a passive messenger between DNA and protein, RNA is a complex molecule involved in regulation at many levels. While the best-known …
