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Description:: Variation in genomes occurs in many forms, from single nucleotide changes to gains and losses of entire chromosomes. Large-scale rearrangements, called structural variants (SVs), are …
Year:: 2013
Contributor:: Ritz, Anna M (creator); Raphael, Benjamin (Director); Dunn, Casey (Reader); Laidlaw, David (Reader); Upfal, Eli (Reader); Brown University. Computer Science (sponsor)
Genre:: theses
Subject:: structural variation; array-comparative genomic hybridization; DNA sequencing
Language:: English
Collection:: Computer Science; Theses and Dissertations

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Description:: Non-allelic homologous recombination (NAHR) plays a major role in genome rearrangement and is implicated in numerous genetic disorders. But detection of NAHR poses a serious …
Year:: 2014
Contributor:: Parks, Matthew (creator); Lawrence, Charles (Director); Thompson, William (Reader); Raphael, Benjamin (Reader); Brown University. Applied Mathematics (sponsor)
Genre:: theses
Subject:: bayesian; bayesian statistics; sequencing; NAHR; genome rearrangement; structural variation; Bayesian statistical decision theory; Statistics
Language:: English
Collection:: Applied Mathematics; Theses and Dissertations

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