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Description:: Neutrophils are the most abundant circulating white blood cell in the human body, and play a crucial role in the innate immune response to infection …
Year:: 2018
Contributor:: Andrews, Christina (creator); Franck, Christian (Advisor); Lefort, Craig (Reader); Reichner, Jonathan (Reader); Wong, Ian (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Immunology; Immune system; Septicemia; Cells--Mechanical properties; soft materials; traction force microscopy
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Description:: The mechanical interaction between the cells and their extracellular matrix (ECM) plays a fundamental role in the various biological process such as cancer metastasis, traumatic …
Year:: 2019
Contributor:: Patel, Mohak (creator); Franck, Christian (Advisor); Henann, David (Reader); Wong, Ian (Reader); Brown University. Engineering: Mechanics of Solids (sponsor)
Genre:: theses
Subject:: Cancer; Cells--Mechanical properties; traction force microscopy; motion tracking
Collection:: Engineering; Mechanics of Solids; Theses and Dissertations

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Description:: The mechanical interaction of neutrophils with the extracellular matrix (ECM) is essential in regulating neutrophil migration to sites of inflammation, a process known as chemotaxis. …
Year:: 2020
Contributor:: Hazlett, Lauren (creator); Franck, Christian (Advisor); Reichner, Jonathan (Reader); Hoffman-Kim, Diane (Reader); Wong, Ian (Reader); Nett, Jeniel (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: traction force microscopy; Neutrophils; mechanobiology; epifluorescence microscopy; Multiphoton excitation microscopy
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

Full Record