Carbohydrate-carbohydrate interactions (CCIs) mediate cell-cell adhesion and are involved in processes that include embryo development, metastasis, and myelin compaction. The main focus of this thesis …
The current reliance on finite fossil fuels for the production of commodity chemicals has been recognized as unsustainable, and therefore has led to increasing pressure …
Cellular redox homeostasis regulates metabolism, cell death, differentiation and development, immune responses, circadian rhythm, and overall cell health. This is achieved through a balance of …
Argentation chromatography is a unique liquid chromatography technique, highly selective for double bonds and their subtle variations (e.g. cis/trans configuration, double bond positioning, etc.). Since …
The overwhelming dependence on fossil fuels for supplying the world’s energy needs is unsustainable, and the rapid depletion of these non-renewable resources has motivated investigations …
The diamagnetic cobalt(III) dimethyl complex, cis,mer-(PMe3)3Co(CH3)2I, was found to promote selective C-C bond formation affording ethane and triplet (PMe3)3CoI. The mechanism of reductive elimination has …
Remediation of ground water contamination associated with industrialization will continue to be a challenge in the 21st century. As the world’s population grows, it’s use …
Abstract of “Monodisperse Nanoparticles for Catalysis” by Sally Fae Ho, Ph.D. Brown University, May 2014 Nanoparticles (NPs) with diameters in the sub-10 nm range have …
Multicomponent reactions (MCRs) are defined as reactions in which more than two starting materials react to form a product that contains the majority of the …
Ubiquitous in chemistry, iron-sulfur proteins carry out many functions vital for survival for the most ancient and modern forms of life, all containing at least …
Atom-transfer reactions can be observed in many biological and industrial processes. Particularly of interest, nitrate and perchlorate reductase are enzymes that can efficiently reduce nitrate …
Pi-bonded organometallic complexes have been intensively studied due to the great variety of metal centers and ligands, which offer great promise for many applications. Pi-bonded …
The surfaces of prokaryotic and eukaryotic cells are covered by glycocalyx which contains a complex network of glycans. Studies continue to reveal that these carbohydrates …
Many naturally occurring peptides and depsipeptides have attracted the interest of medicinal chemists in recent decades due to their broad spectra of bioactivities, such as …
Protein homeostasis is the dynamic process of balancing the constitution of the entire proteome of a living organism. One of the most critical components in …
Scanning tunneling microscopy (STM) at the solid-liquid interface enables structural characterization of monolayers and affords insights into kinetic and thermodynamic influences on the self-assembly process. …
Myelin is a compact multilayer membrane, which is spirally wound around the nerve axons to protect the action potential being transported along the axons from …
Bis arene ruthenium complexes have the ruthenium metal center bonded to the aromatic rings in a π-manner. They have a unique structure with easily functionalized …
A sizeable subset of biologically active and medicinally useful natural products is constituted by peptides. The structural complexities and therapeutic potential of these molecules have …
