Biotechnology

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Description:: Glioblastoma (GBM) is the most common form of primary malignant brain tumor and one of the deadliest types of brain cancer. GBM is a WHO …
Year:: 2024
Contributor:: Real, Jacqueline Nicole (creator); Plavicki, Jessica (Reader); Lawler, Sean (Advisor); Holder, Sheldon (Reader); Brown University. Biology and Medicine: Biotechnology (sponsor)
Genre:: theses
Subject:: Cytomegalovirus infections; Glioblastoma multiforme (GBM); Angiogenesis; Tumor Microenvironment
Collection:: Biology and Medicine; Theses and Dissertations; Biotechnology

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Description:: Background Chordoma is a rare, aggressive cancer with limited treatment options. Chitinase-3-like 1 (CHI3L1), a secreted glycoprotein, is overexpressed in several solid tumors and linked …
Year:: 2026
Contributor:: Wang, Tianyi (creator); Martinez-Moreno, Margot (Advisor); Sullivan, Patricia (Reader); Lawler, Sean (Reader); Brown University. Biology and Medicine: Biotechnology (sponsor)
Genre:: theses
Subject:: Tumor Microenvironment; Cancer--Immunological aspects; Chordoma; Chitinase-3-like 1; immune checkpoint
Collection:: Biology and Medicine; Biotechnology; Theses and Dissertations

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Description:: Introduction: Glioblastoma (GBM) is an aggressive brain tumor with only 5% of patients surviving beyond five years, and it has immunosuppressive tumor microenvironment (TME), which …
Year:: 2026
Contributor:: Qiu, Yanfei (creator); Lawler, Sean (Advisor); Horrigan, Diana (Reader); Cappillino, Gülbenk (Reader); Brown University. Biology and Medicine: Biotechnology (sponsor)
Genre:: theses
Subject:: Glioblastoma multiforme (GBM); Tumor Microenvironment; ADU-S100; STING
Collection:: Biology and Medicine; Theses and Dissertations; Biotechnology

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