Abstract of A Bioengineering Approach to Develop New Technologies for Genomics-Based Healthcare, by Olivia Ott, Sc.M. Brown University, May 2023. Genomics-based healthcare is a rapidly …
Wireless networks of implantable microscale devices are being explored as a means of recording and stimulation of neural activity for various therapeutic applications. Beyond the …
Ischemic heart disease (IHD) is the single leading cause of death in the world and restorative treatment for IHD poses a global healthcare challenge. Myocardial …
In this thesis, the potential success of a novel drug delivery system (PDAL DDS) in the current antifungal DDS market was evaluated. Focus was placed …
Adipose-derived stems cells (ASCs) have key properties such as self-renew and differentiation that makes them a prime candidate to study various issues. An ASC spheroid …
Our research works to 1)understand protective mechanisms for improving sunscreens through the study of ultra violet light absorbers and 2) develop a novel detection and …
Wearable health monitors represent an essential area of research in biomedical engineering, where strain sensors play a major role in enabling effective and continuous health …
Penicillin Binding Protein 5 (PBP5) is a membrane bound transpeptidase that plays an important role in β-lactam antibiotic resistance in Enterococcus faecium. Normally, β-lactams inhibit …
The mammalian tongue consists of a complex array of intersecting muscular components with the capacity to create an extraordinary array of functional geometries and deformations …
When diagnosed in late stages, ovarian cancer is one of the deadliest forms of gynecological cancer. In order to increase the likelihood that a patient …
Bacterial infections can be difficult to treat and potentially lethal due to the rising global threat of antibiotic resistance. Systemic administration and overuse of antibiotics …
The field of medical diagnostics is governed by two practical goals that drive the engineering and relevant innovation necessary to move the technology forward. Firstly, …
Growth factors are recognized as a vital component in the biological repair process, and the strategies developed for in situ tissue engineering and regenerative medicine …
Percutaneous implants are a family of devices that penetrate the skin and suffer from infection-mediated device failure caused by lack of integration/adhesion at the skin/device …
Abstract of Characterization of Pressure-Induced Anisotropy in Atactic Polystyrene, by Derek Rott, ScM, Brown University, May 2019 Atactic polystyrene (aPS) is versatile and cheaply synthesized …
Sigma receptors are a pharmacologically defined class of intracellular orphan receptors that bind a variety of psychotropic agents. The endogenous function of the sigma-2 receptor …
The need to improve the longevity of orthopedic implants in vivo is increasingly important as the annual number of primary hip and knee replacements are …
Multicellular aggregate assembly, whereby individual cells coalesce into a single multicellular structure, is a phenomenon that can model both healthy tissue morphogenesis and cancer pathogenesis. …
The work in this dissertation develops two different biomaterial approaches towards advancing our understanding of how neural cell behavior, specifically migration and proliferation, can respond …
Biofilm formation and drug resistance complicate the treatment of bacterial infections. These infections are comprised of bacteria with low metabolic activity, limiting the effects of …