Description
- Abstract:
- Chronic pain afflicts more than 100 million American adults each year, and there is currently no reliable objective measure of the presence or severity of pain. Using a rodent model of acute and chronic pain, we tested the hypothesis that pain is associated with a pattern of spontaneous (stimulus-independent) electrical brain activity that is quantitatively different from that of a normal, non-pain condition. We also hypothesized that the changes in electrical brain activity associated with chronic pain can be reversed by administration of an experimental T-type calcium-channel blocker Z944.
- Notes:
- Scholarly concentration: Medical Technology, Innovation, and Entrepreneurship
Access Conditions
- Use and Reproduction
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- This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Citation
Lii, Theresa R., LeBlanc, Brian W., and Saab, Carl Y.,
"Using intracranial electrode recordings and electrocorticograhy to characterize how acute and chronic pain alters neural oscillations and connectivity in the rodent brain"
(2016).
Scholarly Concentrations Program Collection of Abstracts.
Brown Digital Repository. Brown University Library.
https://doi.org/10.26300/x7kd-ka25
Relations
Collection:
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Scholarly Concentrations Program Collection of Abstracts
...Each spring the Warren Alpert Medical School of Brown University Scholarly Concentrations Program (SCP) publishes a print volume of abstracts written by medical students in the SCP and their mentors that describes the research projects that they collaborated on over …