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Programming for Organoid Intelligence

Description

Abstract:
Research on human stem cell-derived brain organoids aims to establish organoid intelligence (OI) and promote understanding of human neuronal functioning while avoiding human subject experimentation. Brain organoids are an important model of human brain activity as they provide in vitro reads of functioning human neurons. Utilizing biostatistical inquiry, we loaded in, processed, and analyzed multi-electrode array data collected on brain organoids, to explore molecular mechanisms of learning and memory formation and their computational potential. By directly observing function with our MEA interface, we were able to study real time neural activity. We focused on analyzing basic neuronal spike train data (spikes acquired over time) that will inform the degree of timing and coordination of neural functioning in the organoid.

Access Conditions

Use and Reproduction
All rights reserved
Rights
In Copyright
Restrictions on Use
All Rights Reserved

Citation

Mills, Corina, and Caffo, Brian, "Programming for Organoid Intelligence" (2023). The Leadership Alliance Digital Library. Brown Digital Repository. Brown University Library. https://doi.org/10.26300/5j8m-ye88

Relations

Collection:

  • The Leadership Alliance Digital Library

    A collection of research presentations and posters created by students participating in the Leadership Alliance's Summer Research - Early Identification Program.

    When using this resource, please cite the digital object identifier (DOI) for the specific resource as well as the …

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