Brown University

A Survey of Viral Integration Sites in Hepatocellular Carcinoma

Description

Abstract:
Viral insertions in the human genome have been shown to increase instability and encourage carcinogenesis. Genetic information from viral Hepatitis has been found in hepatocellular carcinoma (HCC). Studies have not previously investigated what other viral integrations are found in HCC. This study found viral information in nearly all of the samples, which could possibly be contributed to contamination. Ignoring contaminants, Hepatitis was found in nearly half of the viral insertions. Older patients with a history of Hepatitis had a greater number of insertions.
Notes:
Scholarly concentration: Medical Technology, Innovation and Entrepreneurship

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Citation

Hsia, Katie L., and Lu, Shaolei, "A Survey of Viral Integration Sites in Hepatocellular Carcinoma" (2018). Warren Alpert Medical School Academic Symposium. Brown Digital Repository. Brown University Library. https://repository.library.brown.edu/studio/item/bdr:833858/

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Collection:

  • Warren Alpert Medical School Academic Symposium

    The Warren Alpert Medical School Academic Symposium is an annual event at Warren Alpert Medical School of Brown University that provides Year II medical students a venue to present their summer research in a poster format. Participation in the Symposium …
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