Oral dosage forms are generally targeting the absorption in the gastrointestinal (GI) tract. For systemic drug delivery, bioavailability of administered drugs is determined by their …
Infectious agents pose a significant threat to global health with profound health and economic implications. Particularly concerning is the emergence of epidemic-competent and life-threatening drug-resistant …
Plant cell walls are composed mainly of carbohydrate containing molecules such as cellulose, hemi-celluloses, various pectins, and proteoglycans. The exact carbohydrate composition varies between species, …
Carbohydrate-carbohydrate interactions (CCIs) between cell surface carbohydrates play an important role in cell adhesion and cell surface signaling. Glycopolymers, synthetic polymers functionalized with carbohydrate pendant …
Metal oxide nanomaterials can be applied to solve problems in areas including medical imaging, catalysis, solid oxide fuels, antioxidant reactions, and the degradation of persistent …
Abstract of "Antioxidant and Antimicrobial Nanoparticles: The Role of Shape, Size and Surface Chemistry" by Yue Hu, Ph.D., Brown University, May 2021 There are many …
Medicine can be divided into two central components: the diagnosis of a disease and its treatment. Both components of medicine are being transformed by the …
Nearly half of the human genome is comprised of mobile genetic elements known as transposons. Most transposons in humans can no longer create new copies …
Streptomycetes are a large group of Gram-positive, soil-dwelling bacteria that have evolved remarkable metabolic capabilities for survival in a nutrient-poor and a biodiverse ecological niche. …
Mass spectrometry has been a long-standing analytical tool for chemists. Tandem mass spectrometry-based proteomics capitalizes on the sensitivity, accuracy, and efficiency of this classic technique …
Poly (lactic-co-glycolic acid) (PLGA) has been widely used as a biomaterial in regenerative medicine due to its good biocompatibility and biodegradability properties. Moreover, nanotopographies have …
Recent studies have demonstrated that any exposure to oxygen during the first hours of life can upregulate oxidative stress and put premature infants at an …
A sizeable subset of biologically active and medicinally useful natural products is constituted by peptides. The structural complexities and therapeutic potential of these molecules have …
Boronic acids are a special class of organic compounds that have been extensively utilized in a wide array of applications due to the unique properties …
Ser/Thr phosphatases dephosphorylate their targets with high specificity, yet the structural determinants of substrate recognition and dephosphorylation are poorly understood. Calcineurin (CN) is a conserved …
Biofilms are communities of bacterial cells that are encapsulated in a self-produced polymeric matrix that can attach to almost any surface [10]. Formation of these …