Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive

This archive is for the long-term preservation and public dissemination of data and digital research products collected and created by researchers associated with Brown University Superfund Research Program Project 2: "Adverse Human Health Impacts of Nanomaterials". Project Leader: Agnes B. Kane, M.D., Ph.D.

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Items (1-9) out of 9 results

A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations.

Description:: Kabadi et al. Particle and Fibre Toxicology (2019) 16:15 https://doi.org/10.1186/s12989-019-0298-0. Multi-walled carbon nanotubes (MWCNT) have been shown to elicit the release of inflammatory and pro-fibrotic …
Contributor:: Kabadi, Pranita K. (creator); Rodd, April L. (creator); Simmons, Alysha E. (creator); Messier, Norma J. (creator); Hurt, Robert H. (creator); Kane, Agnes B. (creator)
Subject:: Three-dimensional imaging; Nanoparticles; Toxicology; Carbon nanotubes
Language:: English
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Project 4: Nanomaterial Design for Environmental Health and Safety; Brown University Superfund Research Program Digital Archive; Brown Superfund Presentations & Publications; Kane Lab Digital Archive and Data Repository; Kane Lab Publications; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive

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Author manuscript: "A 3D fish liver model for aquatic toxicology: Morphological changes and Cyp1a induction in PLHC-1 microtissues after repeated benzo(a)pyrene exposures"

Description:: This is a post-print manuscript of the article allowed by the publisher to be deposited in the Brown Digital Repository. This study characterizes a novel …
Year:: 2017
Contributor:: Rodd, April L. (Author); Messier, Norma J. (Author); Vaslet, Charles A. (Author); Kane, Agnes B. (Author)
Subject:: animal alternatives; cytochrome P450 1A; Cyp1a; fish; hepatocytes; morphology; polycyclic aromatic hydrocarbons; PAHs
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Brown University Superfund Research Program Digital Archive; Brown Superfund Presentations & Publications

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Author manuscript: "Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans"

Thumbnail for Author manuscript: "Evaluating …

Description:: This is a post-print manuscript of the article allowed by the publisher to be deposited in the Brown Digital Repository. The focus of this review …
Year:: 2017
Contributor:: D. Kuempel, Eileen (Author); Jaurand, Marie-Claude (Author); Møller, Peter (Author); Morimoto, Yasuo (Author); Kobayashi, Norihiro (Author); Pinkerton, Kent E. (Author); Sargent, Linda M. (Author); Vermeulen, Roel C. H. (Author); Fubini, Bice (Author); Kane, Agnes B. (Author)
Subject:: Cancer mechanisms; carbon nanofibers; carbon nanotubes; cell proliferation; fibrosis; genotoxicity; inflammation; lung cancer; mesothelioma; particle retention; pulmonary; translocation
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Brown University Superfund Research Program Digital Archive; Brown Superfund Presentations & Publications

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Biodissolution and cellular response to MoO3 nanoribbons and a new framework for early hazard screening for 2D materials.

Thumbnail for Biodissolution and cellular …

Description:: Two-dimensional materials are a class of ultra-thin but highly functional materials that promise improvements in semiconductor electronics, energy capture and storage, or catalysis, as compared …
Year:: 2018
Contributor:: Evan Gray (Author); Browning, Cynthia (Author); Wang, Mengjing (Author); Gion, Kyle (Author); Chao, Eric (Author); Koski, Kristie (Author); Kane, Agnes (Author); Hurt, Robert (Author)
Subject:: 2D nanomaterials; biopersistence; cytotoxicity; nanotoxicity
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Project 4: Nanomaterial Design for Environmental Health and Safety; Brown University Superfund Research Program Digital Archive; Brown Superfund Presentations & Publications; Kane Lab Digital Archive and Data Repository; Kane Lab Publications; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive

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Data from "A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations"

Description:: Data from: Kabadi et al. Particle and Fibre Toxicology (2019) 16:15 https://doi.org/10.1186/s12989-019-0298-0. Multi-walled carbon nanotubes (MWCNT) have been shown to elicit the release of inflammatory …
Year:: 2019
Contributor:: Kabadi, Pranita K. (creator); Rodd, April L. (creator); Simmons, Alysha E. (creator); Messier, Norma J. (creator); Hurt, Robert H. (creator); Kane, Agnes B. (creator)
Subject:: Toxicology; Carbon nanotubes
Language:: English
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Data Products; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 4: Nanomaterial Design for Environmental Health and Safety; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Kane Lab Digital Archive and Data Repository; Kane Lab Data Archive; Brown University Open Data Collection

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Supplementary file for manuscript "Evaluating the Mechanistic Evidence and Key Data Gaps in Assessing the Potential Carcinogenicity of Carbon Nanotubes and Nanofibers in Humans"

Description:: Supplementary files for Eileen D. Kuempel, Marie-Claude Jaurand, Peter Møller, Yasuo Morimoto, Norihiro Kobayashi, Kent E. Pinkerton, Linda M. Sargent, Roel C. H. Vermeulen, Bice …
Year:: 2016
Contributor:: D. Kuempel, Eileen (Creator); Jaurand, Marie-Claude (Creator); Møller, Peter (Creator); Morimoto, Yasuo (Creator); Kobayashi, Norihiro (Creator); Pinkerton, Kent E. (Creator); Sargent, Linda M. (Creator); Vermeulen, Roel C. H. (Creator); Fubini, Bice (Creator); Kane, Agnes B. (Creator)
Subject:: Cancer mechanisms; carbon nanofibers; carbon nanotubes; cell proliferation; fibrosis; genotoxicity; inflammation; lung cancer; mesothelioma; particle retention; pulmonary; translocation
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Data Products; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Brown University Open Data Collection

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Supplementary file from manuscript "A 3D fish liver model for aquatic toxicology: Morphological changes and Cyp1a induction in PLHC-1 microtissues after repeated benzo(a)pyrene exposures"

Description:: Supplementary files for manuscript "A 3D fish liver model for aquatic toxicology: Morphological changes and Cyp1a induction in PLHC-1 microtissues after repeated benzo(a)pyrene exposuresPMID: 28282620 …
Year:: 2016
Contributor:: Rodd, April L. (Creator); Messier, Norma J. (Creator); Vaslet, Charles A. (Creator); Kane, Agnes B. (Creator)
Subject:: animal alternatives; cytochrome P450 1A; Cyp1a; fish; hepatocytes; morphology; polycyclic aromatic hydrocarbons; PAHs
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Data Products; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Brown University Open Data Collection

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Supporting materials for "Biodissolution and Cellular Response to MoO3 Nanoribbons and a New Framework for Early Hazard Screening for 2D Materials"

Thumbnail for Supporting materials for …

Description:: Supplementary files for "Biodissolution and Cellular Response to MoO3 Nanoribbons and a New Framework for Early Hazard Screening for 2D Materials" (DOI: 10.1039/C8EN00362A).
Year:: 2018
Contributor:: Evan Gray (Author); Browning, Cynthia (Author); Wang, Mengjing (Author); Gion, Kyle (Author); Chao, Eric (Author); Koski, Kristie (Author); Kane, Agnes (Author); Hurt, Robert (Author)
Subject:: 2D nanomaterials; biopersistence; cytotoxicity; nanotoxicity
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Data Products; Brown University Open Data Collection; Kane Lab Digital Archive and Data Repository; Kane Lab Data Archive; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive

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Video from manuscript "A 3D fish liver model for aquatic toxicology: Morphological changes and Cyp1a induction in PLHC-1 microtissues after repeated benzo(a)pyrene exposures"

Description:: Video file for manuscript "A 3D fish liver model for aquatic toxicology: Morphological changes and Cyp1a induction in PLHC-1 microtissues after repeated benzo(a)pyrene exposuresPMID: 28282620 …
Year:: 2016
Contributor:: Rodd, April L. (Creator); Messier, Norma J. (Creator); Vaslet, Charles A. (Creator); Kane, Agnes B. (Creator)
Subject:: animal alternatives; cytochrome P450 1A; Cyp1a; fish; hepatocytes; morphology; polycyclic aromatic hydrocarbons; PAHs
Collection:: Brown University Superfund Research Program Digital Archive; Brown Superfund Data Products; Brown University Superfund Research Program Digital Archive; Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive; Brown University Open Data Collection

Full Record

Brown Superfund Project 2: Adverse Human Health Impacts of Nanomaterials Digital Archive

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