Abstract of A Bioengineering Approach to Develop New Technologies for Genomics-Based Healthcare, by Olivia Ott, Sc.M. Brown University, May 2023. Genomics-based healthcare is a rapidly …
Abstract of A Novel NearInfrared Diffuse Optical Spectroscopy System for Stroke Prediction and Diagnosis on the Neck, by Ning Zhang, Degree ScM, Brown University, May …
Tendon and ligament injuries display poor healing capacities from the formation of scar-like tissue resulting in decreased mechanical properties. The application of biomechanics, the study …
In recent years, there has been an exponential growth in biopharmaceutical development stemming from its ability to treat previously incurable diseases and to go from …
Neuroprosthesis research aims to enable communication between the brain and external assistive devices while restoring lost functionality such as occurs from stroke, spinal cord injury …
This dissertation describes translational research conducted to develop a rapid diagnostic for the detection of endotoxin using liquid crystal sensor technology. Due to the elastic …
Molecular diagnostic testing provides critical information to patients that can lead to earlier detection and disease prevention, specific treatment options, and personalized medicine. The workflow …
The overarching goal of this project is to utilize modulated differential scanning calorimetry and hot-stage x-ray diffraction to characterize and quantify the formation of oriented …
Ischemic heart disease (IHD) is a global health burden responsible for the death of millions of people each year. The primary mechanism that drives myocardial …
Despite the existence of metabolomics as a field for nearly two decades, challenges of sample preparation limit the large-scale application and throughput of targeted metabolomics …
Early tissue formation and regeneration is regulated by mechanical forces. However, few tools exist that can measure such forces in situ in cell-dense structures and …
This work aimed to identify the morphological effects of heat and pressure on high molecular weight (300,000 kDa) polyethylene oxide, with a specific focus on …
We worked to develop an analysis system that can process and classify large data sets of audio, specifically infant cries. This clinical project focuses on …
The ability to move magnetic particles at a distance through the use of external magnetic fields has broad implications in drug delivery, soft robotics and …
The revolutionization of capillary electrophoresis (CE) technology has increased research into CE-related issues on long read and ultra-long read lengths for next-generation sequencing (NGS). An …
Cells are rich in a variety of diagnostic information, from morphology to nucleic acid, protein, and metabolite composition. Cells possess more data than any other …
Acute adult hydrocephalus is a buildup of cerebrospinal fluid (CSF) in the ventricles of the brain, and it requires timely, precise, and accurate treatment. In …
Many diagnostic tests are dependent on the effective capture and amplification of nucleic acids. However, the biological samples which contain the target molecules (blood, urine, …