Description
- Abstract:
- Chemotherapy-induced ovarian toxicity is collateral damage that is becoming a leading cause of ovarian insufficiency, which prejudices the patient to premature onset of menopause-associated risks such as osteoporosis, increased cardiovascular risk, and sexual dysfunction in addition to infertility. The purpose of this research study is to determine the immediate gonadotoxic defense mechanisms imparted by multidrug resistant transporters (MDRs) in the two major cell types of the follicle, the granulosa cells and the oocytes by assessing the ovary in situ.
- Notes:
- Scholarly concentration: Women's Reproductive Health
Access Conditions
- Use and Reproduction
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- This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Citation
Voigt, Niesha, Oulhen, Nathalie, Wessel, Gary M., et al.,
"The immediate effects of gonadotoxic agents on the viability of the mammalian ovary: are multidrug resistant transporters protective?"
(2016).
Scholarly Concentrations Program Collection of Abstracts.
Brown Digital Repository. Brown University Library.
https://doi.org/10.26300/sqqe-y390
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Collection:
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Scholarly Concentrations Program Collection of Abstracts
...Each spring the Warren Alpert Medical School of Brown University Scholarly Concentrations Program (SCP) publishes a print volume of abstracts written by medical students in the SCP and their mentors that describes the research projects that they collaborated on over …