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Spherical virus detection using nanoscale capillaries

Description

Abstract:
Nanopores are sensors used to detect DNA and, more recently, filamentous viruses, by measuring electrical current across the nanopore. They have not been used to detect small, spherical viruses, despite how useful that could be. The problem with spherical viruses is that they move quickly and are difficult to detect. This project explores an improved approach to detecting spherical viruses. Using extended nanopores made by heating and pulling hollow silica capillaries, the passage of spherical particles through the capillaries is detected by measuring brief drops in electrical current across the nanopore when it is immersed in a conductive salt solution in an electric field.

Citation

Isik, Oliver, "Spherical virus detection using nanoscale capillaries" (2016). Summer Research Symposium. Brown Digital Repository. Brown University Library. https://doi.org/10.26300/84h2-a678

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Collection:

  • Summer Research Symposium

    Each year, Brown University showcases the research of its undergraduates at the Summer Research Symposium. More than half of the student-researchers are UTRA recipients, while others receive funding from a variety of Brown-administered and national programs and fellowships and go …
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