While information systems are often associated with microelectronic devices, every physical process can be interpreted as an exchange of information. With the slowing of Moore's …
We analyze the feasibility of using light to fragment a peptide into its constituent amino acids before identifying them by mass spectrometry for the purpose …
Nanopore sensors present new opportunities for sequencing DNA in a portable device. The portability of nanopore sequencers allows a user to analyze DNA samples on-site, …
We explore the interactions between engineered nanoscale structures (primarily nanopores and nanotubes) and biomolecules on three inter-related fronts: DNA and protein separation, drug delivery, and …
Nanopore system is important for its many promising applications in rapid DNA sequencing, large biological molecule detection, polynucleotide-enzyme interaction study and etc. Following the first …
It is estimated that 2TW of potential electrical power can be harvested by mixing fresh water and sea water; and while individual nanotubes have demonstrated …
Nanopores are sensors used to detect DNA and, more recently, filamentous viruses, by measuring electrical current across the nanopore. They have not been used to …
There exists a fluidic version of the electrostatic field-effect, by which the transport of ions and charged objects in solution can be controlled in nanoscale …
This thesis presents the development and physical characterization of a nanopore ion source which emits biomolecular ions directly from aqueous solution into vacuum. The primary …
Nanopores can be used as sensors to probe the structure of single polymers. In a typical experiment, a thin insulating membrane containing a nanometer-scale pore …
Solid-state nanopores are an important class of biosensor that can detect the presence of a macromolecule inside the nanopore by a corresponding blockage in the …
Post-translational modifications (PTMs) on amino acids are extremely important to cellular processes as they alter protein properties, but their discovery and localization on novel proteins …