Brown University

Development of a Microelectrode Array and Polymer Sandwich Film for Directed Synapse Formation and Use in a Biohybrid Retinal Prosthesis

Description

Abstract:
There are a variety of challenges that face modern retinal prosthesis designs including electrode cross-talk and retinal-electrode interface separation. We propose a biohybrid retinal prosthesis utilizing axonal bridges and electrical stimulation to improve visual acuity and reduce stimulation threshold levels. We also describe the initial stages of microelectrode fabrication, cell culture, and growth factor release profiling for in-vitro testing of a potential prosthesis and propose future steps for potential design of an implantable device.
Notes:
Scholarly concentration: Medical Technology, Innovation and Entrepreneurship
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Citation

Cheng, Derrick, and Borton, David A., "Development of a Microelectrode Array and Polymer Sandwich Film for Directed Synapse Formation and Use in a Biohybrid Retinal Prosthesis" (2017). Warren Alpert Medical School Academic Symposium. Brown Digital Repository. Brown University Library. https://repository.library.brown.edu/studio/item/bdr:698118/

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Collection:

  • Warren Alpert Medical School Academic Symposium

    The Warren Alpert Medical School Academic Symposium is an annual event at Warren Alpert Medical School of Brown University that provides Year II medical students a venue to present their summer research in a poster format. Participation in the Symposium …
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