Theranostics is the ability to diagnose with greater detail to disease properties and tailor specialized therapeutic regiments to a patient's unique case. Advancements in nanoparticle …
Structural rearrangements within single molecules occur on ultrafast time scales. Many aspects of molecular dynamics, such as the energy flow through excited states, have been …
Post-translational modifications (PTMs) of proteins can have significant effects on different biological processes in which the proteins are involved. Analysis of protein post-translational modifications (PTMs) …
Towards the full understanding the physiology of human Sigma-1 receptor (Sig-1R), we developed a novel ligand-based enrichment strategy and mass spectrometry analysis of the receptor. …
Mass spectrometry has been a long-standing analytical tool for chemists. Tandem mass spectrometry-based proteomics capitalizes on the sensitivity, accuracy, and efficiency of this classic technique …
Recombinant NANS module 2, with DEBS TE appended to the C-terminus, was expressed in Escherichia coli BAP1. Incubation of NANS module 2+DEBS_TE with (2RS) 2 …
The diamagnetic cobalt(III) dimethyl complex, cis,mer-(PMe3)3Co(CH3)2I, was found to promote selective C-C bond formation affording ethane and triplet (PMe3)3CoI. The mechanism of reductive elimination has …
Carbohydrate-carbohydrate interactions (CCIs) make up a separate genre of interactions that have been implicated in intercellular adhesion and signaling. As with most carbohydrate-binding interaction, CCIs …
Over the last decade, there has been increased interest in "nanomaterial", which describes materials with structure on one dimension between 1nm and 100nm. A variety …
Our central goal in this thesis is to investigate the vibrational energy relaxation (VER) of perylene in solution. The size of a perylene molecule makes …
Common resonant spectroscopic methods used to study dynamics in solutions, such as time-dependent fluorescence, share a feature of probing the solute directly, or more precisely …
Common resonant spectroscopic methods used to study dynamics in solutions, such as time-dependent fluorescence, share a feature of probing the solute directly, or more precisely …
Abstract of “Monodisperse Nanoparticles for Catalysis” by Sally Fae Ho, Ph.D. Brown University, May 2014 Nanoparticles (NPs) with diameters in the sub-10 nm range have …
Monodisperse nanocrystals (NCs) currently attract intense research interests because of the novel properties induced by their size, shape, composition and structure. Recent advances in high …
There have been intensive studies on not only the structure of quinonoid metal complexes but also the metal-organometallic coordination polymers by the use of quinone …
Multicomponent reactions (MCRs) are defined as reactions in which more than two starting materials react to form a product that contains the majority of the …
Poly (lactic-co-glycolic acid) (PLGA) has been widely used as a biomaterial in regenerative medicine due to its good biocompatibility and biodegradability properties. Moreover, nanotopographies have …
The volatile metabolite geosmin is a degraded sesquiterpene that is responsible for the characteristic smell of moist soil. Geosmin is produced by a wide range …
We report the preliminary evidence of a novel CH-π interaction between polyethylene glycol and aromatic compounds as well as crown ethers and aromatic compounds. Polyethylene …
Monodisperse nanoparticles (NPs) below 20nm are of intense current interests, not only for the general miniaturization of the size, but also for their novel properties. …
