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Items (1-20) out of 33 results

A Slow Crack Growth Model for High-Density Polyethylene under Thermal and Chemical Environment

Description:: High-density polyethylene (HDPE) is a widely used thermoplastic polymer with application as the material for pipeline transport systems. Due to the longterm, low-stress conditions of …
Year:: 2023
Contributor:: Nam, Hyun Young (creator); Srivastava, Vikas (Advisor); Brown University. Engineering: Mechanics of Solids (sponsor)
Genre:: theses
Subject:: Polymers; Solid Mechanics; Fracture mechanics
Collection:: Engineering; Mechanics of Solids; Theses and Dissertations

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An Investigation of Carbohydrate – Carbohydrate Interactions Using Glycopolymers and Supramolecular Glycoconjugates as Multivalent Model Systems

Description:: Carbohydrate-carbohydrate interactions (CCIs) between cell surface carbohydrates play an important role in cell adhesion and cell surface signaling. Glycopolymers, synthetic polymers functionalized with carbohydrate pendant …
Year:: 2018
Contributor:: Leeber, Blaise William (creator); Basu, Amit (Advisor); Delaney, Sarah (Reader); Sello, Jason (Reader); Brown University. Department of Chemistry (sponsor)
Genre:: theses
Subject:: Polymers; Carbohydrates; Supramolecular chemistry; Carbohydrate-carbohydrate interactions; Self-assembly
Collection:: Chemistry; Theses and Dissertations

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Biological Application of Magnetic Nanoparticles in Targeted Therapeutics and Diagnostics

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Description:: Abstract of "Biological Application of Magnetic Nanoparticles in Targeted Therapeutics and Diagnostics" by Aruna Sigdel, Ph.D., Brown University, May 2014 Theranostics, the combination of diagnosis …
Year:: 2014
Contributor:: Sigdel, Aruna (creator); Sun, Shouheng (Director); Basu, Amit (Reader); Hurt, Robert (Reader); Brown University. Chemistry (sponsor)
Genre:: theses
Subject:: Material Science; Nanomaterials; Bio-sensors; Nanoparticle Characterization; Drug-delivery; Functionalization; Theranostics; Targeting; Magnetic Nanoparticles; Diagnostics; Detection; Materials science; Surface chemistry; Polymers; Nanostructured materials; Nanotechnology; Biosensors; Drug delivery systems
Language:: English
Collection:: Chemistry; Theses and Dissertations

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Characterization Of Temperature-Pressure Induced Morphology in High Molecular Weight Poly (Ethylene Oxide)

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Description:: Abstract of Characterization of Temperature-Pressure Induced Morphology in High Molecular Weight Poly (Ethylene Oxide) by Sheila Velagapudi, ScM., Brown University, May 2020 The focus of …
Year:: 2020
Contributor:: Velagapudi, Sheila (creator); Mathiowitz, Edith (Advisor); Schell, Jacquelyn (Reader); Srivastava, Vikas (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Polymers; poly (ethylene oxide)
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Characterizing Mesophases in Biodegradable Polymers

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Description:: When designing a polymer-based drug delivery system, it is essential that the correct amount of medication is being released to the body’s tissues. This is …
Year:: 2022
Contributor:: Jelynn Tatad (creator); Baptista, Cameron (creator); Chen, Henry (creator); Nagaraj Rao, Apoorva (creator); Mathiowitz, Edith (advisor); Brown University. Karen T. Romer Undergraduate Teaching and Research Awards (research program)
Genre:: posters
Subject:: Biomedical materials; Drugs; Biomedical engineering; Biomaterials; Polymeric drug delivery systems; Polymers; Polylactic acid; Drug delivery systems; Biotechnology; Polymer chemistry
Language:: English
Collection:: Summer Research Symposium

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Deformation and Fracture of Soft Polymers: Experiments, Modeling and Computations

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Description:: Soft polymers constitute a broad class of materials with applications spanning biomedical systems, soft robotics, and impact mitigation. The mechanical properties of these polymers vary …
Year:: 2026
Contributor:: Konale, Aditya Gurusidhappa (creator); Srivastava, Vikas (Advisor); Henann, David (Reader); Guduru, Pradeep (Reader); Bazilevs, Yuri (Reader); LeBlanc, James (Reader); Brown University. Engineering: Mechanics of Solids (sponsor)
Genre:: theses
Subject:: Machine Learning; Polymers; Solid Mechanics; Elastomers; Constitutive Modeling; Finite Element Method (FEM); PINN; Fracture; Soft Polymers
Collection:: Engineering; Mechanics of Solids; Theses and Dissertations

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Denaturing Plastic: The Degradation of Polycarbonates via Enzyme Catalysis

Description:: Plastics are some of the most widely used and discarded materials today. Though convenient, these synthetic polymers have accumulated in soils, oceans, and even our …
Year:: 2020
Contributor:: Lucas Sanchez (creator); Casey, Kerry (creator); Robinson, Jerome (creator); Basu, Amit (creator); Amit Basu (advisor); Brown University. Karen T. Romer Undergraduate Teaching and Research Awards (research program)
Genre:: posters
Subject:: Polymers; Biodegradation; Enzymes
Language:: English
Collection:: Summer Research Symposium

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Design, Fabrication and Evaluation of 2D to 3D nanostructured Ceramic/Polymer Composites for Orthopedic Regeneration and Controlled Drug Delivery

Description:: Desirable cytocompatibility properties of nano-sized ceramics were combined with the tunable degradability and deformability of a select polymer (poly-lactide-co-glycolide, or PLGA) to optimize biological and …
Year:: 2008
Contributor:: Liu, Huinan (creator); Webster, Thomas (director); Morgan, Jeffrey (reader); Mathiowitz, Edith (reader); Palmore, G. Tayhas (reader); Karp, Jeffrey (reader); Brown University. Biomedical Engineering (sponsor)
Genre:: theses
Subject:: nanocomposites; bone tissue engineering; orthopedic applications; surface properties; osteoblast functions; 3D printing; scaffolds; controlled drug delivery; treating bone diseases.; Nanocomposites (Materials); Ceramics; Polymers; Tissue scaffolds; Bone morphogenetic proteins
Language:: English
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Development and characterization of high loaded polymeric nanoparticles to achieve a controlled basal insulin delivery system in the treatment of Diabetes Mellitus

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Description:: Polymeric nanoparticles loaded with insulin is a highly sought-after drug delivery system in the treatment of diabetes mellitus. The goal of this experiment is to …
Year:: 2019
Contributor:: Sukhlal, Shiffoni (creator); Morgan, Jeffrey (Reader); Mathiowitz, Edith (Advisor); Schell, Jacquelyn (Reader); Brown University. Department of Molecular Pharmacology, Physiology and Biotechnology (sponsor)
Genre:: theses
Subject:: Polymers; Diabetes; Drug delivery systems; Polymeric nanoparticles; Insulin
Collection:: Biology and Medicine; Molecular Pharmacology, Physiology, and Biotechnology; Theses and Dissertations

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Developments Toward the Characterization and Quantification of Pressure-Temperature Induced Mesophases in Non-Mesogenic Thermoplastic Polymers

Description:: The overarching goal of this project is to utilize modulated differential scanning calorimetry and hot-stage x-ray diffraction to characterize and quantify the formation of oriented …
Year:: 2018
Contributor:: Baptista, Cameron (creator); Mathiowitz, Edith (Advisor); Tripathi, Anubhav (Reader); Furtado, Stacia (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Polymers; Polymer Films; Biomedical engineering; Polymeric drug delivery systems; Biomedical materials; Materials science
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Effects of Pressure on the Morphology of Semi-Crystalline Polymers

Description:: When exposed to pressures below and above their glass transition temperature (Tg) and melting temperatures (Tm) over time, both the amorphous and crystalline regions of …
Year:: 2016
Contributor:: Baker, Christopher Michael (creator); Morgan, Jeffrey (Reader); Mathiowitz, Edith (Advisor); Tripathi, Anubhav (Reader); Darling, Eric (Reader); Reineke, Joshua (Reader); Brown University. Biology and Medicine: Artificial Organs, Biomaterials, and Cell Technology (sponsor)
Genre:: theses
Subject:: morphology; Biotechnology; Polymers; Polymer Films
Collection:: Biology and Medicine; Artificial Organs, Biomaterials, and Cell Technology; Theses and Dissertations

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Employing a Pendulum Wear-Testing Model to Evaluate the Feasibility of a 3D-Printed Polymer for Small Joint Arthroplasty

Description:: Thumb carpometacarpal osteoarthritis is a degenerative bone condition that affects 20-25% of those over the age of 50. However, conventional surgical repair by metal joint …
Year:: 2019
Contributor:: Navarro, Matthew (Author); Morton, Amy (Author); Crisco, Joseph (Author); Brown University. Alpert Medical School. Scholarly Concentration Program. Non-Scholarly Concentrator (research program)
Subject:: Osteoarthritis; Pendulum; Polymers; Three-dimensional printing; Mechanical wear--Testing; Arthroplasty
Language:: English
Collection:: Warren Alpert Medical School Academic Symposium

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Evaluating the Diffusive Capabilities of Polymeric Nanoparticles in Mucosal Environments

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Description:: Oral drug delivery is a preferred route of administration for medication due to convenience and accessibility. However, due to enzymatic degradation in the gastrointestinal (GI) …
Year:: 2025
Contributor:: Haque, Hena Mariam (creator); Mathiowitz, Edith (Advisor); Darling, Eric (Reader); Shukla, Anita (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Polymers; Nanoparticles; Oral Drug Delivery
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Impact of Pressure and Degradation on Morphology in Mesophase-Inducing Polymer Systems

Description:: Understanding polymer morphology is crucial in innovating new technologies for medical devices. This study focuses on characterizing how polymer blending influences morphology and how these …
Year:: 2025
Contributor:: Tatad, Jelynn Ellianna (creator); Shukla, Anita (Reader); McDonald, Benjamin (Reader); Mathiowitz, Edith (Reader); Brown University. Biology and Medicine: Biotechnology (sponsor)
Genre:: theses
Subject:: morphology; Polymers; Biodegradation; Polymer chemistry; Biomaterials; biodegradable polymers; drug delivery; X-ray diffractometer; Gel permeation chromatography; dolutegravir; meloxicam
Collection:: Biology and Medicine; Biotechnology; Theses and Dissertations

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In vitro and histological analysis of polymer microsphere delivery

Description:: Cellular recruitment has diverse tissue engineering applications, ranging from wound healing to the treatment of metabolic disorders. Chemoattractants encapsulated in hydrogels, microspheres, scaffolds, and other …
Year:: 2016
Contributor:: Yakubov, Jonathan (creator); Zhou, George (creator); Léandre, Vérida (creator); Baker, Christopher (creator); Mathiowitz, Edith (advisor); Brown University. Undergraduate Teaching and Research Award (research program)
Genre:: posters
Subject:: Microspheres; Cell proliferation; Polymers; Histology
Collection:: Summer Research Symposium

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Inducing Mesophase Morphologies In Isotactic Polypropylene

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Description:: This paper investigates the impact of processing conditions, specifically temperature and pressure, on inducing mesophase morphologies in Isotactic Polypropylene (iPP). iPP is a highly valued …
Year:: 2024
Contributor:: Sundaresan, Gayathri (creator); Mathiowitz, Edith (Advisor); Shukla, Anita (Reader); Coulombe, Kareen (Reader); Gray, Marissa (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Polymers; Polymer chemistry
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Induction of mesophase in polycaprolactone and its effect on the long-term delivery of Meloxicam

Description:: Implants are a viable drug delivery vehicle that can provide a consistent release of drug into the blood. Many implants are made with polymers, such …
Year:: 2022
Contributor:: Sharan, Raj (creator); Mathiowtiz, Edith (Advisor); Morgan, Jeffrey (Reader); Darling, Eric (Reader); Brown University. Department of Molecular Pharmacology, Physiology and Biotechnology (sponsor)
Genre:: theses
Subject:: Polymers; Polymeric drug delivery systems; mesophase; long-term drug delivery; Drug delivery devices
Collection:: Biology and Medicine; Molecular Pharmacology, Physiology, and Biotechnology; Theses and Dissertations

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Induction of Mesophase in Polyethylene Glycol and Polyethylene Oxide

Description:: This study examines how molecular weight, temperature, pressure, and the addition of the drugs dolutegravir and curcumin affect the mesophase formation of Polyethylene Glycol (PEG) …
Year:: 2024
Contributor:: Deokule, Yashvi (creator); Mathiowitz, Edith (Advisor); Jong, Yong (Reader); Horrigan, Diana (Reader); Brown University. Biology and Medicine: Biotechnology (sponsor)
Genre:: theses
Subject:: morphology; Polymers; Drug delivery systems; mesophase; Polyethylene glycol; Polyethylene oxide; drug delivery
Collection:: Biology and Medicine; Theses and Dissertations; Biotechnology

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Insights into Pressure-Temperature Induced Morphology and Mesophase Formation in the Non-Mesogenic Polymer Polyethylene Oxide

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Description:: This work aimed to identify the morphological effects of heat and pressure on high molecular weight (300,000 kDa) polyethylene oxide, with a specific focus on …
Year:: 2021
Contributor:: Clevinger, Tobias B (creator); Mathiowitz, Edith (Advisor); Srivastava, Vikas (Reader); Gray, Marissa (Reader); Brown University. Biology and Medicine: Biomedical Engineering (sponsor)
Genre:: theses
Subject:: Polymers; Biomedical engineering; Biomedical materials; Polyethylene oxide
Collection:: Biology and Medicine; Biomedical Engineering; Theses and Dissertations

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Liquid crystal and polymeric coupling and stressed liquid crystal technology for fourier transform spectroscopy

Description:: This dissertation covers fundamental studies and application motivated research exploring the coupling between LC and polymers in unique systems. The interaction of these materials link …
Year:: 2009
Contributor:: Shelton, Leslie (creator); Crawford, Gregory (Director); Pelcovits, Robert (Reader); Jay, Gregory (Reader); Brown University. Physics (sponsor)
Genre:: theses
Subject:: reactive mesogen; FTS; Liquid crystals; Polymers; Phase modulation
Language:: English
Collection:: Physics; Theses and Dissertations

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Items (1-20) out of 33 results

Items (1-20) out of 33 results

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