Postoperative cerebral injuries due to debris traveling up the carotid arteries can be a devastating complications of open-heart surgeries. While the benchmark medical device manufacturers …
All disciplines of biomedical research utilize in vitro models to answer a range of biological questions. Traditional in vitro models, two-dimensional (2D) cell monolayers, fail …
Two-dimensional (2D) materials are a large class of atomically thin, sheet-like solids, whose chemical stability is a critical issue for commercial devices and nanomaterial driven …
Abstract of Disruption of yfjD Gene in Francisella, by Japheth Omonira, ScM., Brown University, May 2018. Francisella tularensis is the causative agent of tularemia, a …
Human tissue regeneration is often characterized by the over-deposition of collagen, resulting in fibrotic scarring. Traditional research into wound healing and fibrosis relies heavily on …
The successful detection and prevention of traumatic brain injuries relies on the quantitative identification of cellular injury thresholds associated with the underlying cellular pathology. First, …
This project aimed (1) to learn the fundamental mechanism of DNA extraction on a novel microfluidic chip that takes advantage of hydrophilic/hydrophobic interactions between sample …
Serous epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy and is associated with accumulation of ascites fluid, which is rich in cell-secreted exosomes. …
Aortic dissection is responsible for significant morbidity and mortality in children, young and older adults. One possible outcome for an artery undergoing dissection is that …
Cell-based therapy is a promising treatment option for central nervous system (CNS) disease and injury, but therapy strategies require optimization to achieve clinical improvement. The …
This paper investigates the impact of processing conditions, specifically temperature and pressure, on inducing mesophase morphologies in Isotactic Polypropylene (iPP). iPP is a highly valued …
Diffuse midline glioma (DMG) is the most aggressive primary brain tumor in children, with <10% surviving more than 2 years post-diagnosis. This tumor is inoperable …
The past quarter-century of biomedical research has seen the emergence of powerful and transformational methods such as quantitative polymerase chain reaction, next generation sequencing, and …
Glioblastoma, classified by the WHO as a grade IV brain tumor, displays highly aggressive and infiltrative properties. Despite the low incidence of the disease as …
Cellular mechanophenotype is defined as the elastic and viscoelastic properties of a cell, and is commonly characterized by atomic force microscopy (AFM). Assessment of a …
Stem cells have shown great promise for the treatment of human disease. However, stem cell therapies are limited by heterogeneous differentiation. As a result, researchers …