Description
- Abstract:
- Biotechnology companies have challenges in their production processes due to the necessity to innovate to gain a competitive edge and meet the demands of the modern world regarding the safety and environmental impact of their processes and products (REBEL Cell Culture Analyzer | 908 Devices, 2023). Creating a strong and reliable control strategy for cell culture processes to keep process performance and finished product quality within strictly defined parameters is one of these technological challenges. In this section, I’ll be addressing the importance of Amino Acids to cell culture, the ARACUS technology which can measure Amino Acid levels, benefits of implementing the ARACUS at AMGEN, a comparison between ARACUS and the standard method for Amino Acid quantification: HPLC, competitors to the ARACUS technology, and the role cell culture process development can play in implementing new technologies such as ARACUS.
- Notes:
- Thesis (Sc. M.)--Brown University, 2024
Citation
Sharoubim, Bishouy,
"Process Analytical Technologies for Small-scale Cell Culture: ARACUS Amino Acid Analyzer"
(2024).
Biotechnology, Biology and Medicine Theses and Dissertations.
Brown Digital Repository. Brown University Library.
https://repository.library.brown.edu/studio/item/bdr:yzgrsszc/
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Biology and Medicine Theses and Dissertations
Theses and Dissertations for the Biology and Medicine department....